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Managing finances in the medical field can be a headache, especially when billing errors and delays occur. As a CFO, you're likely juggling many tasks, and invoicing should be manageable. Medical invoicing software can help as it simplifies billing, reduces errors, and ensures compliance with regulations.

In my experience, finding the right software can transform your billing process. I focus on providing unbiased reviews to help you make informed decisions. You'll find a detailed look at the top medical invoicing tools available, highlighting their features and benefits.

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Best Medical Invoicing Software Summary

This comparison chart summarizes pricing details for my top medical invoicing software selections, helping you find the best one for your budget and business needs.

Tools Price
RXNT From $110/month/provider
CareCloud Pricing upon request
PracticeSuite From $29/user/month
DrChrono From $199/user/month (billed annually)
PrognoCIS From $280/month
CollaborateMD From $279/user/month
ClinicSource From $80/month (for 1 user)
OpenEMR Pricing upon request
AllegianceMD From $850/user/month
iSalus Pricing upon request
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Compare Software Specs Side by Side

Use our comparison chart to review and evaluate software specs side-by-side.

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How To Choose Medical Invoicing Software

It’s easy to get bogged down in long feature lists and complex pricing structures. Here's a checklist of factors to remember to help you stay focused as you work through your unique software selection process.

FactorWhat to Consider
ScalabilityEnsure the software can grow with your practice, handling increased patient volume and billing needs.
IntegrationsCheck if it integrates with your current EHR systems and other tools for seamless data flow.
CustomizabilityLook for software to tailor reports and invoices to fit your specific requirements.
Ease of UseChoose a user-friendly interface to minimize training time for your team.
BudgetCompare pricing plans to find one that fits your budget without sacrificing essential features.
Security SafeguardsVerify that the software complies with HIPAA regulations to ensure patient data protection.

Best Medical Invoicing Software Reviews

Below are my detailed summaries of the best medical invoicing software on my shortlist. My reviews offer a detailed look at each tool’s key features, pros and cons, integrations, and ideal use cases to help you find the best one for you.

Best for cloud-based access

  • Free demo available
  • From $110/month/provider
Visit Website
Rating: 4.2/5

RXNT is a cloud-based medical practice management software catering to healthcare providers looking for flexibility in accessing their billing and scheduling services. It offers practice management and billing solutions to streamline operations and improve efficiency.

Why I picked RXNT: The cloud-based nature allows your team to access the system from anywhere with an internet connection, making it versatile for remote work. Features like electronic prescribing and real-time insurance eligibility checks simplify daily operations. The system's integrated billing and scheduling help maintain organized workflows. This flexibility and accessibility make it a good choice for practices needing remote capabilities.

Standout features & integrations:

Features include appointment reminders, a customizable dashboard, and financial reporting tools. Appointment reminders reduce no-shows and improve patient attendance. The customizable dashboard allows your team to prioritize tasks, while financial reporting tools offer insights into practice performance.

Integrations include Surescripts, Change Healthcare, TriZetto, Navicure, Quest Diagnostics, LabCorp, and Updox.

Pros and cons

Pros:

  • Customizable dashboard
  • Real-time insurance checks
  • Cloud-based access

Cons:

  • Requires stable internet connection
  • Initial learning curve

Best for large practices

  • Pricing upon request
Visit Website
Rating: 3.7/5

CareCloud is a medical billing and practice management software for large healthcare practices. It supports comprehensive revenue cycle management, enhancing sizable teams' billing accuracy and operational efficiency.

Why I picked CareCloud: It's ideal for large practices, offering scalable solutions that grow with your business. Features like revenue cycle management and analytics tools provide insights into financial performance. The software's patient engagement capabilities help maintain strong patient relationships. These functions ensure your team manages complex billing processes effectively.

Standout features & integrations:

Features include analytics dashboards for insights into practice performance, enabling data-driven decisions. Patient engagement tools improve communication and enhance patient satisfaction. Appointment scheduling keeps your team organized and reduces missed appointments.

Integrations include Surescripts, LabCorp, Quest Diagnostics, Zocdoc, Updox, DrFirst, Change Healthcare, AdvancedMD, and Practice Fusion.

Pros and cons

Pros:

  • Robust revenue cycle management
  • Efficient appointment scheduling
  • Strong patient engagement features

Cons:

  • Limited offline capabilities
  • Initial setup complexity

Best for multi-location support

  • Free demo available
  • From $29/user/month
Visit Website
Rating: 4.3/5

PracticeSuite is a medical billing and practice management software designed to support healthcare providers with multiple locations. It serves practices of various sizes by offering billing, scheduling, and patient management features.

Why I picked PracticeSuite: It supports multi-location practices, allowing your team to efficiently manage operations across different sites. Features such as centralized scheduling and billing help keep everything organized. The software includes reporting tools that provide insights into practice performance across locations, making it ideal for growing practices with more than one office.

Standout features & integrations:

Features include appointment reminders to reduce no-shows and improve patient attendance. Enabling patient portal access enhances engagement by allowing patients to manage appointments and records. Maintain electronic health records to keep patient information organized and easily accessible.

Integrations include QuickBooks, Kareo, AdvancedMD, Athenahealth, DrChrono, Practice Fusion, eClinicalWorks, Allscripts, Greenway Health, and Cerner.

Pros and cons

Pros:

  • Scalable for growing practices
  • Centralized scheduling
  • Multi-location support

Cons:

  • Dependent on internet connectivity
  • Limited offline capabilities

Best for mobile invoicing

  • Free demo available
  • From $199/user/month (billed annually)
Visit Website
Rating: 3.5/5

DrChrono is a medical billing and practice management software designed for healthcare providers who require mobile access. It serves clinics and practices by offering billing, scheduling, and patient management tools, all accessible via mobile devices.

Why I picked DrChrono: The software's mobile invoicing capability allows your team to manage billing and patient records on the go. Features like electronic health records and appointment scheduling are seamlessly integrated into its mobile app. This mobility ensures that you can access critical information anytime, anywhere. Your practice benefits from flexibility and efficiency, particularly if you're often away from the office.

Standout features & integrations:

Features include customizable forms to tailor documentation to your needs. Real-time eligibility checks streamline billing by instantly verifying patient insurance. Telemedicine options expand your practice's reach, enabling virtual consultations with patients.

Integrations include Square, Box, Updox, Surescripts, Change Healthcare, CoverMyMeds, Twilio, Quest Diagnostics, LabCorp, and Zocdoc.

Pros and cons

Pros:

  • Customizable documentation forms
  • Real-time eligibility checks
  • Mobile access for invoicing

Cons:

  • May need additional training
  • Requires stable internet connection

Best for compliance features

  • Free demo available
  • From $280/month
Visit Website
Rating: 3.5/5

PrognoCIS is a medical billing and electronic health record (EHR) software tailored for healthcare providers looking for comprehensive compliance features. It serves clinics and practices by streamlining billing and patient management tasks, ensuring adherence to regulatory standards.

Why I picked PrognoCIS: Its compliance features help your team meet healthcare regulations effortlessly. The software includes HIPAA-compliant billing and documentation, reducing the risk of non-compliance. You can benefit from features like electronic prescribing and patient portal access, enhancing patient care and operational efficiency. These compliance-focused tools make it a reliable choice for practices prioritizing regulatory adherence.

Standout features & integrations:

Features include telemedicine capabilities for virtual consultations expanding patient access. Customizable templates allow you to tailor documents to specific needs. Access detailed reporting tools for insights into practice performance, helping you make informed decisions.

Integrations include Surescripts, LabCorp, Quest Diagnostics, Updox, DrFirst, Change Healthcare, and CoverMyMeds.

Pros and cons

Pros:

  • Customizable documentation templates
  • Telemedicine capabilities
  • Electronic prescribing included

Cons:

  • Limited offline access
  • Higher learning curve

Best for real-time updates

  • Free demo available
  • From $279/user/month
Visit Website
Rating: 4.4/5

CollaborateMD is a cloud-based medical billing and practice management software ideal for small to medium-sized healthcare providers. It assists users with billing, scheduling, and patient management tasks, enhancing daily operational efficiency.

Why I picked CollaborateMD: It provides real-time updates, ensuring your team has the most up-to-date information for billing and scheduling. Features like claim tracking and patient payment reminders help reduce errors and improve cash flow. The software's cloud-based nature allows access from anywhere, making it flexible for remote work. 

Standout features & integrations:

Features include customizable reports, patient payment reminders, and claim-tracking tools. Customizable reports let your team generate insights tailored to your needs. Patient payment reminders help reduce missed payments, while claim tracking tools keep billing processes organized.

Integrations include MDTech, LabCorp, Quest Diagnostics, and Practice Fusion. 

Pros and cons

Pros:

  • Claim tracking features
  • Cloud-based flexibility
  • Real-time updates

Cons:

  • Limited offline features
  • Learning curve for new users

Best for therapy practices

  • Free demo available
  • From $80/month (for 1 user)

ClinicSource is a therapy billing and practice management software tailored for therapy practices, offering tools for scheduling, documentation, and invoicing. It serves therapists and therapy clinics by streamlining administrative tasks and enhancing workflow efficiency.

Why I picked ClinicSource: It's specifically designed to meet the needs of therapy practices, providing features like therapy-specific documentation and scheduling tools. These features help your team manage appointments and maintain detailed patient records. The software also includes invoicing capabilities tailored for therapy billing. This focus on therapy practice needs makes it an excellent option for therapists seeking specialized solutions.

Standout features & integrations:

Features include customizable templates, treatment planning tools, and progress tracking. Customizable templates let your team create documentation suited to your therapy style. Treatment planning tools ensure organized care plans, while progress tracking helps monitor patient outcomes effectively.

Integrations include QuickBooks, Office Ally, Zirmed, Availity, and Apex EDI.

Pros and cons

Pros:

  • Integrated treatment planning
  • Customizable documentation templates
  • Tailored for therapy practices

Cons:

  • Dependent on internet connectivity
  • May need additional training

Best for open-source flexibility

  • Free demo available
  • Pricing upon request
Visit Website
Rating: 4/5

OpenEMR is an open-source medical invoicing software for healthcare providers and medical practices. It helps manage patient records, billing, and scheduling in a customizable environment.

Why I picked OpenEMR: It's open-source, allowing you to modify and adapt the software to fit your specific needs. This flexibility is a big draw for practices looking to tailor their system without extra costs. It includes patient demographics, medical records management, and billing capabilities. The open-source nature ensures you control updates and customizations, making it ideal for tech-savvy teams.

Standout features & integrations:

Features include customizable templates, multi-language support, and a patient portal. These features help your team manage diverse patient needs and improve communication. The patient portal offers secure messaging and appointment scheduling, enhancing patient interaction.

Integrations include LabCorp, Quest Diagnostics, NewCrop, Updox, ZH Healthcare, and DrFirst.

Pros and cons

Pros:

  • Responsive community support
  • Customizable interface
  • Open-source flexibility

Cons:

  • Frequent updates needed
  • Complex initial setup

Best for AI-driven billing

  • Free demo available
  • From $850/user/month

AllegianceMD is a cloud-based medical billing and practice management software for healthcare providers seeking advanced billing solutions. It serves small to medium-sized practices by automating billing processes and improving revenue cycle management.

Why I picked AllegianceMD: The AI-driven billing feature helps your team optimize claim submissions and reduce errors. It includes tools for appointment scheduling and patient records, simplifying administrative tasks. The software's real-time analytics provide insights into financial performance. This intelligent billing system offers efficiency and accuracy, making it suitable for practices focused on maximizing revenue.

Standout features & integrations:

Features include customizable reporting, patient engagement tools, and electronic health records management. Customizable reporting allows your team to tailor financial insights to your needs. Patient engagement tools enhance communication, while electronic health records keep patient information organized.

Integrations include Surescripts, LabCorp, Quest Diagnostics, Change Healthcare, Updox, and DrFirst.

Pros and cons

Pros:

  • Cloud-based access
  • Real-time financial analytics
  • AI-driven billing automation

Cons:

  • May need additional training
  • Limited offline capabilities

Best for integrated EHR

  • Free demo available
  • Pricing upon request

iSalus is medical billing software for healthcare providers that offers integrated EHR and practice management services. It caters to small and medium-sized practices, helping them streamline billing and patient record management.

Why I picked iSalus: The integration of EHR within its billing system provides a unified solution for managing patient data and billing processes. This tool offers features like appointment scheduling, claims management, and electronic prescriptions. These features ensure your team maintains efficient workflows and accurate patient records. The integrated EHR functionality saves time and reduces errors, making it a solid choice for practices needing both billing and patient management.

Standout features & integrations:

Features include patient portal access, customizable reporting, and telehealth capabilities. The patient portal enhances communication and engagement with patients. Customizable reporting allows you to tailor financial and operational insights to your needs.

Integrations include Surescripts, LabCorp, Quest Diagnostics, Practice Fusion, Updox, and DrFirst.

Pros and cons

Pros:

  • Patient portal enhances engagement
  • Suitable for medium-sized practices
  • Customizable reporting features

Cons:

  • Limited scalability for large practices
  • EHR integration may require training

Other Medical Invoicing Software

Here are some additional medical invoicing software options that didn’t make it onto my shortlist but are still worth checking out.

  1. EZClaim

    Best for small practices

  2. Charmhealth

    Best for customizable workflows

  3. AdvancedMD

    Best for integrated telemedicine

  4. Practice Fusion

    Best for small clinics

  5. eClinicalWorks

    Best for patient engagement tools

  6. Greenway Health

    Best for customizable reporting

  7. Oracle Health

    Best for large-scale operations

  8. Veradigm

    Best for data-driven insights

  9. NextGen Healthcare

    Best for specialty practices

  10. Atheahealth

    Best for cloud-based practice management

Medical Invoicing Software Selection Criteria

When selecting the best medical invoicing software for this list, I considered everyday buyer needs and pain points, such as billing accuracy and compliance with healthcare regulations. I also used the following framework to keep my evaluation structured and fair.

Core Functionality (25% of total score)
To be considered for inclusion in this list, each solution had to fulfill these everyday use cases:

  • Generate and manage invoices
  • Process insurance claims
  • Track patient billing information
  • Ensure compliance with regulations
  • Integrate with EHR systems

Additional Standout Features (25% of total score)
To help further narrow down the competition, I also looked for unique features, such as:

  • Telemedicine billing support
  • Real-time eligibility checks
  • Customizable reporting tools
  • Integration with mobile apps
  • AI-driven billing insights

Usability (10% of total score)
To get a sense of the usability of each system, I considered the following:

  • Intuitive user interface
  • Minimal training requirements
  • Clear navigation paths
  • Responsive design
  • Consistent performance

Onboarding (10% of total score)
To evaluate the onboarding experience for each platform, I considered the following:

  • Availability of training videos
  • Interactive product tours
  • Access to chatbots for assistance
  • Comprehensive webinars
  • Pre-made templates

Customer Support (10% of total score)
To assess each software provider’s customer support services, I considered the following:

  • Availability of 24/7 support
  • Access to live chat
  • Quality of phone support
  • Comprehensive knowledge base
  • Prompt response times

Value For Money (10% of total score)
To evaluate the value for money of each platform, I considered the following:

  • Competitive pricing structure
  • Range of features offered
  • Flexibility in pricing plans
  • Discounts for annual subscriptions
  • Transparent pricing policies

Customer Reviews (10% of total score)
To get a sense of overall customer satisfaction, I considered the following when reading customer reviews:

  • Overall satisfaction ratings
  • Feedback on customer support
  • Frequency of positive mentions
  • Commonly reported issues
  • Testimonials from similar-sized practices

In my research, I sourced countless product updates, press releases, and release logs from different medical invoicing software vendors. Here are some of the emerging trends I’m keeping an eye on.

  • AI-Driven Analytics: Vendors incorporate AI to provide deeper insights into billing patterns. This helps practices identify inefficiencies and optimize revenue cycles. For example, some platforms offer predictive analytics to forecast payment delays.
  • Telehealth Billing Integration: As telehealth becomes more common, medical invoicing software is adapting to include specialized billing for virtual visits. This ensures accurate billing for services that occur outside traditional office settings.
  • Blockchain for Security: A few forward-thinking vendors are exploring blockchain to enhance data security and integrity. This trend aims to build trust by ensuring that billing data is tamper-proof and verifiable.
  • Value-Based Care Models: Software is tailored to support value-based care billing, focusing on patient outcomes rather than services rendered. This trend aligns billing practices with the shift toward more patient-centric care.
  • Patient Self-Service Options: More tools now offer patient portals where users can manage billing, view statements, and make payments online. This trend caters to the growing demand for transparency and convenience in patient interactions.

What Is Medical Invoicing Software?

Medical invoicing software helps healthcare providers manage billing and payment processes. Doctors, medical office managers, and billing specialists use these tools to reduce errors and improve efficiency. Features like electronic billing, patient portals, and compliance checks support accurate invoicing and enhance patient interaction. These tools offer significant value by saving time, reducing administrative burdens, and ensuring timely payments.

Features Of Medical Invoicing Software

When selecting medical invoicing software, look for the following key features.

  • Reimbursement Management: Streamlines the reimbursement process by accurately tracking claims and ensuring timely payments from insurance companies.
  • Integration with EMR: Connects seamlessly with Electronic Medical Records (EMR) systems to ensure efficient data flow between clinical and billing processes.
  • Billing Services: Offers billing services for both individual practitioners and large billing companies, streamlining invoicing and claims management.
  • Clearinghouse Integration: Connects with clearinghouses to facilitate faster and more efficient claims processing, reducing administrative workload.
  • Charge Capture: Automates charge capture to minimize revenue loss by recording and submitting all billable services promptly.
  • Insurance Company Coordination: Manages and verifies insurance information to simplify claims submissions and reduce denials.
  • Payers Management: Keeps track of payer requirements and automates the submission process to various insurance payers.
  • RCM (Revenue Cycle Management): Provides features for claims submission, denial management, and accounts receivable tracking to maximize profitability.
  • Accounts Receivable Tracking: Monitors outstanding payments and provides tools to follow up on unpaid invoices, improving cash flow and financial health.
  • Electronic Remittance Advice: Processes electronic remittance advice (ERA) to automatically post payments and manage adjustments.
  • Financial Health Reports: Generates insights into the practice's financial health, helping identify areas for optimizing revenue.
  • Practice Management System Integration: Integrates with practice management systems for a comprehensive solution, managing patient information, scheduling, and billing.
  • Web-Based Access: Provides a web-based platform for healthcare providers and billers to access the system from anywhere, ensuring flexibility and convenience.
  • Backups and Data Security: Includes regular data backups and advanced security features to protect sensitive patient and financial information.

Benefits Of Medical Invoicing Software

Implementing medical invoicing software provides several benefits for your team and your business. Here are a few you can look forward to.

  • Improved accuracy: Reduces billing errors through automated processes, ensuring accurate invoicing.
  • Faster payments: Speeds up payment collection with electronic billing and patient portals, enhancing cash flow.
  • Regulatory compliance: Ensures adherence to healthcare regulations with built-in compliance checks, minimizing penalties.
  • Enhanced patient experience: Provides patients with easy access to billing information and payment options through patient portals.
  • Increased efficiency: Automates routine billing tasks, allowing your team time to focus on patient care.
  • Financial insights: Offers analytics and reporting tools that provide valuable insights into your practice's economic performance.
  • Adaptability to trends: Supports telehealth and value-based care models, keeping your practice aligned with industry shifts.

Costs And Pricing Of Medical Invoicing Software

Selecting medical invoicing software requires understanding the various pricing models and plans available. Costs vary based on features, team size, add-ons, and more. The table below summarizes standard plans, average prices, and typical features of medical invoicing software solutions.

Plan Comparison Table for Medical Invoicing Software

Plan TypeAverage PriceCommon Features
Free Plan$0Basic invoicing, limited reporting, and patient portals.
Personal Plan$10-$30/user/monthElectronic billing, real-time eligibility checks, and basic analytics.
Business Plan$50-$100/user/monthAdvanced reporting, compliance checks, and telehealth billing support.
Enterprise Plan$70-$150/user/monthFull customization, dedicated support, and AI-driven analytics.
A breakdown of plan types, costs, and features for medical invoicing software.

Medical Invoicing Software FAQs

Here are some answers to common questions about the best medical billing software.

How does medical invoicing software work?

Medical billing and invoicing software automates billing tasks and optimizes business processes. It handles patient billing, claims management, and payment tracking, reducing manual effort. By automating these tasks, your team can save time and reduce errors. This software also offers reporting features to help you track financial performance and compliance.

How might accounting and medical invoicing software be used in an office?

Accounting and billing software in a medical office streamlines tasks like patient accounts and collections. It manages back-office functions such as accounts payable and receivable. With these tools, you can enhance patient management, claims processing, and financial operations. The software helps reduce administrative workload and improve accuracy.

Can medical invoicing software integrate with EHR systems?

Yes, most medical billing software can integrate with EHR systems. These integrations allow for data transfer between billing and patient records. This ensures that your team can access accurate patient information, improving billing accuracy. Integration helps streamline operations and reduce duplicate data entry.

What are the security considerations for medical invoicing software?

Medical billing software must comply with healthcare regulations to protect patient data. Look for software with encryption and access controls to ensure data security. Your team should also consider software that provides audit logs and regular updates. Security features help maintain compliance and protect sensitive information.

How do I choose the right medical invoicing software for my practice?

Choosing the right software depends on your practice’s needs and budget. Consider features like billing automation, compliance checks, and reporting tools. Evaluate the software’s ease of use and integration capabilities with your existing systems. It is essential to select a solution that aligns with your practice’s workflow and goals.

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Simon Litt
By Simon Litt

Simon Litt is the editor of The CFO Club, specializing in covering a range of financial topics. His career has seen him focus on both personal and corporate finance for digital publications, public companies, and digital media brands across the globe.